The Human Lysosome Gene Database

The Lysosome Gene Database is an ongoing effort to catalogue genes encoding lysosomal proteins. For each lysosomal gene, LGDB provides information on :

miRNA-genes interactions
master gene transcription factor EB (TFEB) CLEAR binding motif and binding sites

View only genes reported lysosomal by of the following sources:

A gene network regulating lysosomal biogenesis and function.
Sardiello M, Science 2009

The human urine mannose 6-phosphate glycoproteome.
Sleat DE, Biochim Biophys Acta 2007

Integral and associated lysosomal membrane proteins.
Schröder B, Traffic 2007

Identification and validation of mannose 6-phosphate glycoproteins in human plasma reveal a wide range of lysosomal and non-lysosomal proteins.
Sleat DE, Mol Cell Proteomics 2006

Identification of sites of mannose 6-phosphorylation on lysosomal proteins.
Sleat DE, Mol Cell Proteomics 2006

The human brain mannose 6-phosphate glycoproteome: a complex mixture composed of multiple isoforms of many soluble lysosomal proteins.
Sleat DE, Proteomics 2005

Proteomic analysis of human lysosomes: application to monocytic and breast cancer cells.
Journet A, Proteomics 2002

Towards a human repertoire of monocytic lysosomal proteins.
Journet A, Electrophoresis 2000

Two-dimensional mapping and microsequencing of lysosomal proteins from human placenta.
Chataway TK, Placenta 1998

Reactome: a knowledge base of biologic pathways and processes.
Vastrik I, Genome Biol 2007

UniProt archive.
Leinonen R, Bioinformatics 2004

KEGG: kyoto encyclopedia of genes and genomes.
Kanehisa M, Nucleic Acids Res 2000

Gene ontology: tool for the unification of biology. The Gene Ontology Consortium.
Ashburner M, Nat Genet 2000

The proteome of lysosomes.
Schröder BA, Proteomics 2010

Proteomics of the lysosome.
Lübke T, Biochim Biophys Acta 2009

Characterization of the CLEAR network reveals an integrated control of cellular clearance pathways.
Palmieri M, Hum Mol Genet 2011

miRanda
pictar4w
pictar5w
PITA
TargetScan
miRTarBase*
* exp. verified targets

The Human Lysosome Gene Database

Filter genes

Filter algorithms

Order

Filter miRNAs

hsa-let-7
hsa-let-7a
hsa-let-7b
hsa-let-7c
hsa-let-7d
hsa-let-7e
hsa-let-7f
hsa-let-7g
hsa-let-7i
hsa-let-98
hsa-miR-1
hsa-miR-10
hsa-miR-100
hsa-miR-101
hsa-miR-103
hsa-miR-105
hsa-miR-106
hsa-miR-106a
hsa-miR-106b
hsa-miR-107
hsa-miR-10a
hsa-miR-10b
hsa-miR-1178
hsa-miR-1179
hsa-miR-1182
hsa-miR-1183
hsa-miR-1184
hsa-miR-1185
hsa-miR-1192
hsa-miR-1197
hsa-miR-1200
hsa-miR-1201
hsa-miR-1202
hsa-miR-1203
hsa-miR-1204
hsa-miR-1205
hsa-miR-1206
hsa-miR-1207-3p
hsa-miR-1207-5p
hsa-miR-1208
hsa-miR-122
hsa-miR-1224-3p
hsa-miR-1225-3p
hsa-miR-1225-5p
hsa-miR-1226
hsa-miR-1227
hsa-miR-1228
hsa-miR-1229
hsa-miR-122a
hsa-miR-1231
hsa-miR-1233
hsa-miR-1234
hsa-miR-1236
hsa-miR-1237
hsa-miR-124
hsa-miR-1243
hsa-miR-1244
hsa-miR-1245
hsa-miR-1246
hsa-miR-1248
hsa-miR-124a
hsa-miR-125
hsa-miR-1251
hsa-miR-1252
hsa-miR-1253
hsa-miR-1255a
hsa-miR-1255b
hsa-miR-1256
hsa-miR-1257
hsa-miR-1258
hsa-miR-1259
hsa-miR-125a
hsa-miR-125a-3p
hsa-miR-125a-5p
hsa-miR-125b
hsa-miR-126
hsa-miR-126-a
hsa-miR-126-r
hsa-miR-126-s
hsa-miR-126-star
hsa-miR-126-t
hsa-miR-1260
hsa-miR-1261
hsa-miR-1262
hsa-miR-1263
hsa-miR-1264
hsa-miR-1266
hsa-miR-1267
hsa-miR-1268
hsa-miR-1269
hsa-miR-127-3p
hsa-miR-127-5p
hsa-miR-1270
hsa-miR-1271
hsa-miR-1272
hsa-miR-1274a
hsa-miR-1274b
hsa-miR-1275
hsa-miR-1276
hsa-miR-1278
hsa-miR-1279
hsa-miR-128
hsa-miR-1282
hsa-miR-1283
hsa-miR-1284
hsa-miR-1285
hsa-miR-1286
hsa-miR-1287
hsa-miR-1288
hsa-miR-128a
hsa-miR-128b
hsa-miR-129
hsa-miR-129-3p
hsa-miR-129-5p
hsa-miR-1290
hsa-miR-1292
hsa-miR-1293
hsa-miR-1294
hsa-miR-1297
hsa-miR-1299
hsa-miR-130
hsa-miR-1300
hsa-miR-1301
hsa-miR-1302
hsa-miR-1303
hsa-miR-1304
hsa-miR-1305
hsa-miR-1306
hsa-miR-1308
hsa-miR-130a
hsa-miR-130b
hsa-miR-130b-3p
hsa-miR-132
hsa-miR-1321
hsa-miR-1322
hsa-miR-1323
hsa-miR-1324
hsa-miR-133
hsa-miR-133a
hsa-miR-133b
hsa-miR-134
hsa-miR-135
hsa-miR-135a
hsa-miR-135b
hsa-miR-136
hsa-miR-137
hsa-miR-138
hsa-miR-138-5p
hsa-miR-139
hsa-miR-139-5p
hsa-miR-140
hsa-miR-140-3p
hsa-miR-140-5p
hsa-miR-141
hsa-miR-142-3p
hsa-miR-142-5p
hsa-miR-143
hsa-miR-144
hsa-miR-145
hsa-miR-146
hsa-miR-146a
hsa-miR-146b
hsa-miR-146b-3p
hsa-miR-146b-5p
hsa-miR-147
hsa-miR-148
hsa-miR-148a
hsa-miR-148b
hsa-miR-149
hsa-miR-15
hsa-miR-150
hsa-miR-152
hsa-miR-153
hsa-miR-154
hsa-miR-155
hsa-miR-15a
hsa-miR-15b
hsa-miR-16
hsa-miR-17
hsa-miR-17-5p
hsa-miR-181
hsa-miR-181a
hsa-miR-181b
hsa-miR-181c
hsa-miR-181d
hsa-miR-182
hsa-miR-182-a
hsa-miR-182-r
hsa-miR-182-s
hsa-miR-182-star
hsa-miR-182-t
hsa-miR-1825
hsa-miR-1826
hsa-miR-1827
hsa-miR-183
hsa-miR-184
hsa-miR-185
hsa-miR-186
hsa-miR-187
hsa-miR-188
hsa-miR-188-3p
hsa-miR-188-5p
hsa-miR-18a
hsa-miR-18b
hsa-miR-19
hsa-miR-190
hsa-miR-190b
hsa-miR-191
hsa-miR-192
hsa-miR-193a
hsa-miR-193a-3p
hsa-miR-193b
hsa-miR-194
hsa-miR-195
hsa-miR-196a
hsa-miR-196b
hsa-miR-197
hsa-miR-198
hsa-miR-199
hsa-miR-199-5p
hsa-miR-199a
hsa-miR-199a-3p
hsa-miR-199a-5p
hsa-miR-199a-a
hsa-miR-199a-r
hsa-miR-199a-s
hsa-miR-199a-star
hsa-miR-199a-t
hsa-miR-199b
hsa-miR-199b-3p
hsa-miR-199b-5p
hsa-miR-19a
hsa-miR-19b
hsa-miR-20
hsa-miR-200a
hsa-miR-200b
hsa-miR-200c
hsa-miR-202
hsa-miR-202-3p
hsa-miR-203
hsa-miR-204
hsa-miR-205
hsa-miR-206
hsa-miR-208
hsa-miR-208a
hsa-miR-208b
hsa-miR-20a
hsa-miR-20b
hsa-miR-21
hsa-miR-210
hsa-miR-211
hsa-miR-212
hsa-miR-214
hsa-miR-215
hsa-miR-216
hsa-miR-216a
hsa-miR-216b
hsa-miR-217
hsa-miR-218
hsa-miR-218-5p
hsa-miR-219
hsa-miR-219-1-3p
hsa-miR-219-2-3p
hsa-miR-219-5p
hsa-miR-22
hsa-miR-220b
hsa-miR-220c
hsa-miR-221
hsa-miR-222
hsa-miR-223
hsa-miR-224
hsa-miR-23a
hsa-miR-23b
hsa-miR-24
hsa-miR-25
hsa-miR-26a
hsa-miR-26b
hsa-miR-27a
hsa-miR-27b
hsa-miR-28
hsa-miR-28-5p
hsa-miR-290-5p
hsa-miR-292-5p
hsa-miR-296-3p
hsa-miR-296-5p
hsa-miR-297
hsa-miR-298
hsa-miR-299-3p
hsa-miR-299-5p
hsa-miR-29a
hsa-miR-29b
hsa-miR-29c
hsa-miR-300
hsa-miR-301
hsa-miR-301a
hsa-miR-301b
hsa-miR-302
hsa-miR-302a
hsa-miR-302a-a
hsa-miR-302a-r
hsa-miR-302a-s
hsa-miR-302a-star
hsa-miR-302a-t
hsa-miR-302b
hsa-miR-302b-a
hsa-miR-302b-r
hsa-miR-302b-s
hsa-miR-302b-star
hsa-miR-302b-t
hsa-miR-302c
hsa-miR-302c-a
hsa-miR-302c-r
hsa-miR-302c-s
hsa-miR-302c-star
hsa-miR-302c-t
hsa-miR-302d
hsa-miR-302e
hsa-miR-302f
hsa-miR-30a
hsa-miR-30a-3p
hsa-miR-30a-5p
hsa-miR-30b
hsa-miR-30b-5p
hsa-miR-30c
hsa-miR-30d
hsa-miR-30e
hsa-miR-30e-3p
hsa-miR-30e-5p
hsa-miR-31
hsa-miR-32
hsa-miR-320
hsa-miR-320a
hsa-miR-320b
hsa-miR-320c
hsa-miR-320d
hsa-miR-323
hsa-miR-323-3p
hsa-miR-323-5p
hsa-miR-324-3p
hsa-miR-324-5p
hsa-miR-326
hsa-miR-328
hsa-miR-329
hsa-miR-33
hsa-miR-330
hsa-miR-330-3p
hsa-miR-330-5p
hsa-miR-331
hsa-miR-331-3p
hsa-miR-335
hsa-miR-335-5p
hsa-miR-337-3p
hsa-miR-338
hsa-miR-338-3p
hsa-miR-338-5p
hsa-miR-339
hsa-miR-339-3p
hsa-miR-339-5p
hsa-miR-33a
hsa-miR-33b
hsa-miR-340
hsa-miR-340-5p
hsa-miR-342
hsa-miR-342-3p
hsa-miR-342-5p
hsa-miR-345
hsa-miR-346
hsa-miR-34a
hsa-miR-34b
hsa-miR-34b-5p
hsa-miR-34c
hsa-miR-34c-3p
hsa-miR-34c-5p
hsa-miR-351
hsa-miR-361
hsa-miR-361-3p
hsa-miR-361-5p
hsa-miR-362-3p
hsa-miR-362-5p
hsa-miR-363
hsa-miR-365
hsa-miR-367
hsa-miR-368
hsa-miR-369-3p
hsa-miR-370
hsa-miR-371-5p
hsa-miR-372
hsa-miR-373
hsa-miR-373-3p
hsa-miR-374
hsa-miR-374a
hsa-miR-374b
hsa-miR-375
hsa-miR-376
hsa-miR-376a
hsa-miR-376b
hsa-miR-376b-3p
hsa-miR-376c
hsa-miR-377
hsa-miR-378
hsa-miR-379
hsa-miR-380
hsa-miR-381
hsa-miR-382
hsa-miR-383
hsa-miR-384
hsa-miR-384-3p
hsa-miR-384-5p
hsa-miR-409-3p
hsa-miR-409-5p
hsa-miR-410
hsa-miR-411
hsa-miR-412
hsa-miR-421
hsa-miR-422a
hsa-miR-423-3p
hsa-miR-423-5p
hsa-miR-424
hsa-miR-425
hsa-miR-429
hsa-miR-431
hsa-miR-432
hsa-miR-433
hsa-miR-448
hsa-miR-449
hsa-miR-449a
hsa-miR-449b
hsa-miR-449c
hsa-miR-450a
hsa-miR-450b-3p
hsa-miR-450b-5p
hsa-miR-451
hsa-miR-451a
hsa-miR-452
hsa-miR-453
hsa-miR-454
hsa-miR-455
hsa-miR-455-3p
hsa-miR-455-5p
hsa-miR-484
hsa-miR-485
hsa-miR-485-3p
hsa-miR-485-5p
hsa-miR-486-3p
hsa-miR-486-5p
hsa-miR-487a
hsa-miR-487b
hsa-miR-488
hsa-miR-489
hsa-miR-490
hsa-miR-490-3p
hsa-miR-490-5p
hsa-miR-491-3p
hsa-miR-491-5p
hsa-miR-494
hsa-miR-495
hsa-miR-496
hsa-miR-497
hsa-miR-498
hsa-miR-499
hsa-miR-499-3p
hsa-miR-499-5p
hsa-miR-500
hsa-miR-501-3p
hsa-miR-501-5p
hsa-miR-502-3p
hsa-miR-502-5p
hsa-miR-503
hsa-miR-504
hsa-miR-505
hsa-miR-505.h
hsa-miR-505.m
hsa-miR-506
hsa-miR-507
hsa-miR-508-3p
hsa-miR-508-5p
hsa-miR-509-3-5p
hsa-miR-509-3p
hsa-miR-509-5p
hsa-miR-511
hsa-miR-512-3p
hsa-miR-512-5p
hsa-miR-513a-3p
hsa-miR-513a-5p
hsa-miR-513b
hsa-miR-513c
hsa-miR-514
hsa-miR-515-3p
hsa-miR-515-5p
hsa-miR-516a-3p
hsa-miR-516a-5p
hsa-miR-517b
hsa-miR-518a-3p
hsa-miR-518a-5p
hsa-miR-518b
hsa-miR-518c
hsa-miR-518d-3p
hsa-miR-518d-5p
hsa-miR-518f
hsa-miR-519.d
hsa-miR-519a
hsa-miR-519b-3p
hsa-miR-519b-5p
hsa-miR-519c-3p
hsa-miR-519c-5p
hsa-miR-519d
hsa-miR-519e
hsa-miR-520a-3p
hsa-miR-520a-5p
hsa-miR-520b
hsa-miR-520c-3p
hsa-miR-520c-5p
hsa-miR-520d-3p
hsa-miR-520d-5p
hsa-miR-520e
hsa-miR-520f
hsa-miR-520g
hsa-miR-520h
hsa-miR-521
hsa-miR-522
hsa-miR-524-5p
hsa-miR-525-5p
hsa-miR-526a
hsa-miR-526b
hsa-miR-527
hsa-miR-532-3p
hsa-miR-532-5p
hsa-miR-539
hsa-miR-541
hsa-miR-542
hsa-miR-542-3p
hsa-miR-542-5p
hsa-miR-543
hsa-miR-544
hsa-miR-545
hsa-miR-548a-3p
hsa-miR-548a-5p
hsa-miR-548b-3p
hsa-miR-548b-5p
hsa-miR-548c-3p
hsa-miR-548c-5p
hsa-miR-548d-3p
hsa-miR-548d-5p
hsa-miR-548e
hsa-miR-548f
hsa-miR-548g
hsa-miR-548h
hsa-miR-548i
hsa-miR-548j
hsa-miR-548k
hsa-miR-548l
hsa-miR-548m
hsa-miR-548n
hsa-miR-548o
hsa-miR-548p
hsa-miR-549
hsa-miR-550
hsa-miR-551a
hsa-miR-551b
hsa-miR-552
hsa-miR-553
hsa-miR-554
hsa-miR-555
hsa-miR-556-3p
hsa-miR-556-5p
hsa-miR-557
hsa-miR-559
hsa-miR-561
hsa-miR-562
hsa-miR-563
hsa-miR-564
hsa-miR-567
hsa-miR-568
hsa-miR-569
hsa-miR-570
hsa-miR-571
hsa-miR-573
hsa-miR-574-3p
hsa-miR-574-5p
hsa-miR-575
hsa-miR-576-3p
hsa-miR-576-5p
hsa-miR-577
hsa-miR-578
hsa-miR-579
hsa-miR-580
hsa-miR-581
hsa-miR-582-3p
hsa-miR-582-5p
hsa-miR-583
hsa-miR-584
hsa-miR-585
hsa-miR-586
hsa-miR-587
hsa-miR-588
hsa-miR-589
hsa-miR-590
hsa-miR-590-3p
hsa-miR-590-5p
hsa-miR-591
hsa-miR-592
hsa-miR-593
hsa-miR-595
hsa-miR-597
hsa-miR-599
hsa-miR-600
hsa-miR-601
hsa-miR-603
hsa-miR-604
hsa-miR-605
hsa-miR-606
hsa-miR-607
hsa-miR-608
hsa-miR-609
hsa-miR-610
hsa-miR-611
hsa-miR-612
hsa-miR-613
hsa-miR-615-3p
hsa-miR-615-5p
hsa-miR-616
hsa-miR-618
hsa-miR-619
hsa-miR-620
hsa-miR-622
hsa-miR-623
hsa-miR-624
hsa-miR-625
hsa-miR-626
hsa-miR-628-3p
hsa-miR-628-5p
hsa-miR-629
hsa-miR-630
hsa-miR-631
hsa-miR-632
hsa-miR-633
hsa-miR-634
hsa-miR-635
hsa-miR-636
hsa-miR-637
hsa-miR-640
hsa-miR-641
hsa-miR-642
hsa-miR-643
hsa-miR-644
hsa-miR-645
hsa-miR-646
hsa-miR-647
hsa-miR-648
hsa-miR-649
hsa-miR-651
hsa-miR-653
hsa-miR-654-3p
hsa-miR-654-5p
hsa-miR-655
hsa-miR-656
hsa-miR-657
hsa-miR-659
hsa-miR-660
hsa-miR-661
hsa-miR-663
hsa-miR-663b
hsa-miR-664
hsa-miR-665
hsa-miR-699
hsa-miR-7
hsa-miR-708
hsa-miR-744
hsa-miR-758
hsa-miR-760
hsa-miR-761
hsa-miR-765
hsa-miR-766
hsa-miR-767-3p
hsa-miR-767-5p
hsa-miR-768-3p
hsa-miR-768-5p
hsa-miR-769-3p
hsa-miR-769-5p
hsa-miR-770-5p
hsa-miR-7a
hsa-miR-7b
hsa-miR-802
hsa-miR-873
hsa-miR-874
hsa-miR-875-3p
hsa-miR-875-5p
hsa-miR-876-3p
hsa-miR-876-5p
hsa-miR-877
hsa-miR-882
hsa-miR-885-3p
hsa-miR-885-5p
hsa-miR-888
hsa-miR-890
hsa-miR-891b
hsa-miR-892a
hsa-miR-892b
hsa-miR-9
hsa-miR-9-a
hsa-miR-9-r
hsa-miR-9-s
hsa-miR-9-star
hsa-miR-9-t
hsa-miR-92
hsa-miR-920
hsa-miR-921
hsa-miR-922
hsa-miR-924
hsa-miR-92a
hsa-miR-92b
hsa-miR-93
hsa-miR-93.m
hsa-miR-93.r
hsa-miR-933
hsa-miR-934
hsa-miR-935
hsa-miR-936
hsa-miR-938
hsa-miR-939
hsa-miR-940
hsa-miR-942
hsa-miR-943
hsa-miR-944
hsa-miR-96
hsa-miR-98
hsa-miR-99a
hsa-miR-99a-5p
hsa-miR-99b
hsa-miR-99b-5p